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Original Article : 대한치과기재학회지 31(2):105-114, 2004


골내 고정 장치용 초내식성 스테인리스강 내식성 및

세포독성



1연세대학교 치과대학 치과생체재료공학 교실 및 연구소, 2연세대학교 치과대학 교정과학교실 

3연세대학교 공과대학 금속시스템공학과


오근택1 ․강국진2 ․손병화2 ․박용수3 ․김경남1





Corrosion Resistance and Cytotoxicity of Super Stainless Steels

for Skeletal Anchorage System


Keun-Taek Oh1, Kook-Jin Kang2, Byeong-Hwa Sohn2, Yong-Soo Park3, and Kyoung-Nam Kim1


1Department and Research Institute of Dental Biomaterials and Bioengineering, College of Dentistry, 

Yonsei University, Seoul 120-752, Korea

2Department of Orthodontics, College of Dentistry, Yonsei University, Seoul 120-752, Korea

3Department of Metallurgical Engineering, Yonsei University, Seoul 120-749, Korea


Received January 02, 2004 ; Accepted May 11, 2004

  Nickel is one of the most common causes of allergic contact dermatitis and hypersensitivity. In case of stainless steel as a biomaterial, the higher the corrosion resistance and the lower the content, the better it is for the human body. However, because nickel plays an essential role in the stabilization of the austenitic phase and in the corrosion resistance of stainless steel, it is difficult to exclude the nickel from the constituents of stainless steels. Therefore, the purpose of this study was to investigate corrosion resistance and cytotoxicity of super stainless steels, with respect to nickel content and to evaluate their potential for skeletal anchorage system.

  In terms of corrosion resistance, super stainless steels exhibited lower passive current density(2~4μA/cm) than pure Ti(6.6μA/cm) in the body-sumulated solution and similar potentiodynamic polarization behaviors to each other. Pitting corrosion occurred in 316LSS, but not in the orthers. Open circuit potentials of annealed super stainless steels were higher than those of the cold rolled, and they were  increased significantly soon after being immersed into the solution. In potentiostatic test, current densities of super stainless steels decreased abruptly soon after potential-loaded at 250mV(SCE), which meaned these steels had high corrosion resistance in a human body. In addition, SR-50A, super stainless steel, exhibited no cytotoxicity, while the others exhibited slight cytotoxicity in agar overlay test and they all exhibited cell viability of more than 87% in MTT test. It means that super stainless steels are slightly cytotoxic to the fibroblast cell. They did not cause any significantly adverse effect on osteoblast cell proliferation. These indicated that the cytotoxicity of super stainless steels are free or slight due to their high corrosion resistance. The cytotoxicity had no relations with nickel contents, because even SR-50A with the highest nickel content exhibited no cytotoxicity. Because super duplex and ferritic stainless steels containing small amount of nickel showed high corrosion resistance, they can minimize the adverse effect of nickel when used in a human body.



Key Words : Super stainless steels, nickel, passive film, corrosion resistance, cytotoxicity

J Korean Res Soc Dent Mater 31(2):105-114, 2004


주소 : 서울시 서대문구 신촌동 134 우편번호 120-752

       연세대학교 치과대학 치과생체재료공학 교실 및 연구소, 김경남

ISSN : 1225-1631

* 이 논문은 2004년도 두뇌한국 21 사업 연세대학교 의과학 사업단 및 한국과학재단 MRC 프로그램(R13-2003-013)과 국가지정 연구실 사업에 의하여 지원되었음.



 

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